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CAR Enhancers: A Novel Advance in CAR-T Cell Therapy
Elizabeth Chen ’28 Since the 2017 FDA approval of tisagenlecleucel, commonly known as Kymriah, for the treatment of patients under the age of 25 with relapsed or refractory acute lymphocytic leukemia, research in the field of CAR-T cell therapy has continued to rapidly develop. CAR-T cell therapy is a gene therapy using CAR-T cells: T-cells…
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Shedding Light on Challenges Associated with SSRI Antidepressant Medication Withdrawal
Dana Ayebare ’27 Mahmood, Raqeeb & Wallace, Vuokko & Wiles, Nicola & Kessler, David & Button, Katherine & Fairchild, Graeme. (2024). The lived experience of withdrawal from Selective Serotonin Reuptake Inhibitor (SSRI) antidepressants: A qualitative interview study. Health Expectations. 27. 10.1111/hex.13966. Introduction Antidepressants are increasing in use and cultural relevance in the West. After the…
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Bridging the Gap: Addressing Challenges in Pediatric Medical Device Innovation
Alexander Steele ’28 Medical devices play a crucial role in the diagnosis and treatment of disease in children, but the development, testing, and approval of pediatric devices lags behind that of adult technology. Despite the reality that delivery rooms and neonatal intensive care units are technology-heavy care settings, the Food and Drug Administration’s 2017 report…